From beginning to end, 2025 was a year of devastation for scientists in the United States.
January saw the abrupt suspension of key operations across the National Institutes of Health, not only disrupting clinical trials and other in-progress studies but stalling grant reviews and other activities necessary to conduct research. Around the same time, the Trump administration issued executive orders declaring there are only two sexes and ending DEI programs. The Trump administration also removed public data and analysis tools related to health disparties, climate change and environmental justice, among other databases.
February and March saw a steep undercutting of federal support for the infrastructure crucial to conducting research as well as the withholding of federal funding from several universities.
And over the course of the following months, billions of dollars of grants supporting research projects across disciplines, institutions and states were terminated. These include funding already spent on in-progress studies that have been forced to end before completion. Federal agencies, including NASA, the Environmental Protection Agency, the National Oceanic and Atmospheric Administration and the U.S. Agency for International Development have been downsized or dismantled altogether.
The Conversation asked researchers from a range of fields to share how the Trump administration’s science funding cuts have affected them. All describe the significant losses they and their communities have experienced. But many also voice their determination to continue doing work they believe is crucial to a healthier, safer and more fair society.
Pipeline of new scientists cut off
Carrie McDonough, Associate Professor of Chemistry, Carnegie Mellon University
People are exposed to thousands of synthetic chemicals every day, but the health risks those chemicals pose are poorly understood. I was a co-investigator on a US$1.5 million grant from the EPA to develop machine-learning techniques for rapid chemical safety assessment. My lab was two months into our project when it was terminated in May because it no longer aligned with agency priorities, despite the administration’s Make America Healthy Again report specifically highlighting using AI to rapidly assess childhood chemical exposures as a focus area.
Labs like mine are usually pipelines for early-career scientists to enter federal research labs, but the uncertain future of federal research agencies has disrupted this process. I’m seeing recent graduates lose federal jobs, and countless opportunities disappear. Students who would have been the next generation of scientists helping to shape environmental regulations to protect Americans have had their careers altered forever.
Many researchers are working to advocate for science in the public sphere.
John McDonnell/AP Photo
I’ve been splitting my time between research, teaching and advocating…



